Program

Registration onsite from 10:00 am

Program XIV International Symposium on Vasoactive Peptides
FRIDAY – 11/17/2023
2:00 – 2:15 p.m.OPENING SESSION
Robson Santos – Symposium Chair
Raphael Escorsim Szawka – Coordinator of the Graduate Program in Biological Sciences: Physiology and Pharmacology – UFMG
2:15 – 3:30 p.m.SESSION I
Chair: Maria José Campagnole-Santos; Michael Bader
2:15 – 2:45 p.m.The vasopeptidase world – from the RAS to Long Covid.
Anthony Turner, UK 
2:45 – 3:15 p.m.Targeting strategies for ACE2 ubiquitination in diseases.
Eric Lazartigues, USA. 
3:15 – 3:30 p.m.Oral presentation I:
Angiotensin-(1-7) Improve Early Host Immune Responses, And Exerts Pro-Resolving Effects In A Model Of Severe Dengue Infection.
Viviane Lima Batista, Federal University of Minas Gerais, Brazil
3:30 – 3:45 p.m.COFFEE BREAK
3:45 – 5:45 p.m.SESSION II 
Chair: Maria Luiza Chaves; Ulrike Steckelings
3:45 – 4:15 p.m.Single cell analysis of the Renin Angiotensin System in the paraventricular nucleus of hypothalamic during hypertension and obesity.
Yumei Feng Earley, USA. 
4:15 – 4:45 p.m.Anti-inflammatory response of Mas receptor: dialogue with other receptors.
Mariela Gironacci, Argentina.
4:45 – 5:15 p.m.Inhibitors of SGLT-2 cotransporters: beyond Glycemic Control.
Maria Cláudia Irigoyen, Brazil. 
5:15 – 5:45 p.m.Is there an endogenous AT2-receptor agonist? Latest data on angiotensin-(1-5).
Ulrike Steckelings, Denmark.
6:00 – 8:00 p.m.POSTER SESSION
SATURDAY– 11/18/2023
9:00 – 10:30 a.m.SESSION III 
Chair: Edilamar Oliveira; Patricia Gallagher
9:00 – 9:30 a.m.Angiotensin-(1-7): a novel pharmacological tool against vascular ageing?
Concepción Peiró, Spain. 
9:30 – 10:00 a.m.Developmental origins of cardiovascular diseases after preterm birth: from bench to bedside and back.
Anne Monique Nuyt, Canada. 
10:00 – 10:30 a.m.Metabolically stable apelin analogs in hyponatremia and heart failure after myocardial infarction.
Catherine Llorens-Cortes, France. 
10:30 – 10:45 a.m.COFFEE BREAK
10:45- 12:45 p.m.SESSION IV 
Chair: Carlos Castro; Jan Danser.
10:45 – 11:15 a.m.Interplay between Ang-(1-7) and endothelin – a novel vasoprotective mechanism.
Rhian Touyz, Canada. 
11:15 – 11:45 a.m.Apelin receptor axis – a novel therapeutic pathway in preeclampsia.
Liliya Yamaleyeva, USA. 
11:45 – 12:15 p.m.Dysfunction of the Renin-Angiotensin-Aldosterone System in Septic Shock.
Mark Chappell, USA. 
12:15 – 12:30 p.m.Oral presentation II:
Elastase-2 Expression In Human Abdominal Aortic Aneurysms: A Novel Finding In Disease Pathogenesis.
Vinicius Flora Dugaich, Ribeirão Preto Medical School, University of São Paulo, Brazil
12:30 – 12:45 p.m.Oral presentation III :
Angiotensin-(1-7), A Potential Adjuvant To Doxorubicin Cancer Therapy, Reduces Nephrotoxicity By Decreasing Oxidative Stress And Fibrosis.
Ana Clara Melo, Wake Forest University, USA
12:45 – 2:00 p.m.LUNCH BREAK
2:00 – 4:00 p.m.SESSION V 
Chair: Maria de Fátima Leite; Patricia Chakur Brum
2:00 – 2:30 p.m.Hypertension treatment by immunotherapy. The new frontier.
Carlos Ferrario, USA. 
2:30 – 3:00 p.m.The first retro-enantiomers for the RAS.
María Paz Ocaranza, Chile. 
3:00 – 3:30 p.m.Novel antihypertensives, and in particular angiotensinogen siRNA.
Jan Danser, USA. 
3:30 – 4:00 p.m.Angiotensin-(1-7): A Prospective Cancer Therapeutic.
Patricia Gallagher, USA. 
4:00 – 4:15 p.m.COFFEE BREAK
4:15  – 6:15 p.m.SESSION VI
Chair: Eric Lazartigues; Lucíola Barcelos
4:15 – 4:45 p.m.Angiotensin-(1-7) and the Vasculogenic Function of CD34+ cells in Diabetes: Role of Telomerase Reverse Transcriptase.
Yagna Jarajapu, USA.
4:45 – 5:15 p.m.RAS manipulation in the critically ill patient.
Filippo Annoni, Belgium. 
5:15 – 5:45 p.m.Angiotensin peptides in the uterus: Paracrine actions beyond circulation.
Fernando Reis, Brazil. 
5:45 – 6:00 p.m.Oral presentation IV:
Sympathetic Neural Overactivity, Endothelial Dysfunction, Aortic Stiffening, And Diminished Exercise Capacity In Breast Cancer Survivors Treated With Doxorubicin And Trastuzumab-Based Chemotherapy.
João Eduardo Izaias, D’Or Institute for Research and Education, Brazil
6:00 – 6:15 p.m.Oral presentation V:
Reduced Renal Hepcidin Clearance Contributes To Anemia In Angiotensinogen Deficient Mice.
André F. Rodrigues, Max Delbrück Center, Germany
6:15 – 6:45 p.m.MrgD knock-out mice: new molecular and functional findings.
Thiago Verano Braga, Brazil.
SUNDAY– 11/19/2023
9:00 – 10:00 a.m.SESSION VII 
Chair: Kátia De Angelis; Anna Monique Nuyt.
9:00 – 9:30 a.m.The role of Angiotensin-(1-7)/MasR axis in preclinical models of infectious diseases.
Lirlândia Sousa, Brazil.
9:30 – 10:00 a.m.Cellular and molecular mechanisms in the development of heart failure with preserved ejection fraction.
Sergio Lavandero, Chile.
10:00 – 10:15 a.m.COFFEE BREAK
10:15 – 12:00 p.m.SESSION VIII 
Chair: Dulce Casarini; Rike Kemplin
10:15 – 10:30 a.m.Oral presentation VI:
Assessment Of Gene Expression Of MAS And MRGD Receptors In The Nasal Epithelium Of Eutrophic And Obese Individuals Infected With SARS-Cov-2. 
Jonathan Lopes Moreira, Federal University of the Jequitinhonha and Mucuri Valleys, Brazil
10:30 – 10:45 a.m.Oral presentation VII:
The new MAS receptor agonist, CGEN-856S, activates nitric oxide signaling in cardiomyocytes.
Kiany Miranda, Federal University of Minas Gerais
10:45 – 11:15 a.m.Functional autoantibodies against the angiotensin II AT1- and angiotensin 1-7 MAS receptor in SARS-CoV-2 infected patients with long-COVID symptoms.
Gerd Wallukat, Germany.
11:15 – 11:45 a.m.Carboxypeptidases as potential drug targets: News on CPM and ACE2.
Michael Bader, Germany.
12:00 p.m.Awards Session and Closing Ceremony 
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